Formula: C5H10Br2. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Synthesis and biological evaluation of thiazolidinedione derivatives of chalcones and flavones as antihyperglycemic and antidyslipidemic agents. Author is Satyanarayana, Mavurapu; Shukla, Poonam; Tripathi, Brajendra K.; Tiwari, Priti; Srivastava, Arvind K.; Pratap, Ram.
A series of chalcone and flavone derivatives I [R1 = 4-MeOC6H4, 1,3-benzodioxol-5-yl; n = 2, 3] II [R = 3,5-di-OCH2Ph, 3,4-di-OCH2Ph, 3,4,5-tri-MeO, 3,4-di-MeO, 3,5-di-MeO; n = 1, 2] based on 2,4-thiazolidinedione had been synthesized and evaluated for in vivo antihyperglycemic activity in sucrose loaded (SLM) and streptozotocin (STZ) induced diabetic animal models and also for antidyslipidemic activity in the triton model. Compounds II [R = 3,4,5-tri-MeO, 3,4-di-MeO, 3,5-di-MeO; n = 2] exhibited potent blood glucose-lowering activity in both SLM and STZ models. Compounds I [R1 = 1,3-benzodioxol-5-yl; n = 3], and II [R = 3,4,5-tri-MeO, 3,4-di-MeO, 3,5-di-MeO; n = 1, 2] showed moderate lipid-lowering activity. The selected most potent compounds I [R1 = 1,3-benzodioxol-5-yl; n = 3] and II [R = 3,4,5-tri-MeO; n = 2] were also studied in db/db mice for both antihyperglycemic and antidyslipidemic activity.
Here is just a brief introduction to this compound(111-24-0)Formula: C5H10Br2, more information about the compound(1,5-Dibromopentane) is in the article, you can click the link below.
Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis