The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Aminoquinazolin-4(3H)-one( cas:20198-19-0 ) is researched.Formula: C8H7N3O.Rifkin, Jared L.; Wali, Abdul W. published the article 《Effects of pteridines on the filopodia of Dictyostelium discoideum vegetative amebae》 about this compound( cas:20198-19-0 ) in Cell Motility and the Cytoskeleton. Keywords: Dictyostelium filopodia pteridine chemotaxis. Let’s learn more about this compound (cas:20198-19-0).
Living vegetative amebas of NC-4H D. discoideum were studied to determine if a variety of pteridines had any effect on the filopodia. Production, elongation, and branching of these filopodia were stimulated by pteridines that are chemoattractants for cells of this strain. This stimulation occurred at chemotactically effective concentrations and was observed before motility was evident. A relationship between filopodia and chemoattractant signal processing is discussed.
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Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis