Category: 1663-45-2

SDS of cas: 1663-45-2. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 1,2-Bis(diphenylphosphino)ethane, is researched, Molecular C26H24P2, CAS is 1663-45-2, about Carboxylation of a Palladacycle Formed via C(sp3)-H Activation: Theory-Driven Reaction Design. Author is Kanna, Wataru; Harabuchi, Yu; Takano, Hideaki; Hayashi, Hiroki; Maeda, Satoshi; Mita, Tsuyoshi.

Theory-driven organic synthesis is a powerful tool for developing new organic transformations. A palladacycle(II), generated from 8-methylquinoline via C(sp3)-H activation, is frequently featured in the scientific literature, albeit that the reactivity toward CO2, an abundant, inexpensive, and non-toxic chem., remains elusive. Authors have theor. discovered potential carboxylation pathways using the artificial force induced reaction (AFIR) method, a d.-functional-theory (DFT)-based automated reaction path search method. The thus obtained results suggest that the reduction of Pd(II) to Pd(I) is key to promote the insertion of CO2. Based on these computational findings, they employed various one-electron reductants, such as Cp*2Co, a photoredox catalyst under blue LED irradiation, and reductive electrolysis ((+)Mg/(-)Pt), which afforded the desired carboxylated products in high yields. After screening phosphine ligands under photoredox conditions, they discovered that bidentate ligands such as dppe promoted this carboxylation efficiently, which was rationally interpreted in terms of the redox potential of the Pd(II)-dppe complex as well as on the grounds of DFT calculations They are convinced that these results could serve as future guidelines for the development of Pd(II)-catalyzed C(sp3)-H carboxylation reactions with CO2.

This literature about this compound(1663-45-2)SDS of cas: 1663-45-2has given us a lot of inspiration, and I hope that the research on this compound(1,2-Bis(diphenylphosphino)ethane) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Townrow, Oliver P. E.; Chung, Cheuk; Macgregor, Stuart A.; Weller, Andrew S.; Goicoechea, Jose M. published an article about the compound: 1,2-Bis(diphenylphosphino)ethane( cas:1663-45-2,SMILESS:P(CCP(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4 ).Related Products of 1663-45-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1663-45-2) through the article.

We report on the synthesis of an alkane-soluble Zintl cluster, [η4-Ge9(Hyp)3]Rh(COD) (I), that can catalytically hydrogenate cyclic alkenes such as 1,5-cyclooctadiene and cis-cyclooctene. This is the first example of a well-defined Zintl-cluster-based homogeneous catalyst.

From this literature《A Neutral Heteroatomic Zintl Cluster for the Catalytic Hydrogenation of Cyclic Alkenes》,we know some information about this compound(1663-45-2)Related Products of 1663-45-2, but this is not all information, there are many literatures related to this compound(1663-45-2).

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 1663-45-2, is researched, SMILESS is P(CCP(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4, Molecular C26H24P2Journal, Nanoscale Advances called Halogen effects on the electronic and optical properties of Au13 nanoclusters, Author is Gao, Ze-Hua; Dong, Jia; Zhang, Qian-Fan; Wang, Lai-Sheng, the main research direction is gold13 nanocluster halogen effect electronic optical property.Synthetic Route of C26H24P2.

We report an exptl. and theor. investigation of the electronic and optical properties of a series of icosahedral Au13 nanoclusters, protected using different halogen ligands (Cl, Br, and I), as well as 1,2-bis(diphenylphosphino)ethane (dppe) ligands. All three clusters are comprised of the same Au13 kernel with two halogens coordinated to the poles of the icosahedral cluster along with five dppe ligands. UV-vis absorption spectra indicate a systematic red shift from Cl to Br to I, as well as a sudden enhancement of the second excitonic peak for the I-coordinated cluster. D. functional theory (DFT) calculations suggest that all clusters possess a wide HOMO-LUMO energy gap of ~1.79 eV and are used to assign the first two excitonic bands. Frontier orbital analyses reveal several HOMO → LUMO transitions involving halogen-to-metal charge transfers. For the I-coordinated cluster, more complicated I-to-metal charge transfers give rise to different excitation features observed exptl. The current findings show that halogen ligands play important roles in the electronic structures of gold clusters and can be utilized to tune the optical properties of the clusters.

There is still a lot of research devoted to this compound(SMILES：P(CCP(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)Synthetic Route of C26H24P2, and with the development of science, more effects of this compound(1663-45-2) can be discovered.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Tetrahedral Cu(I) complexes as electrocatalysts for the reduction of protons to dihydrogen gas, published in 2021-07-07, which mentions a compound: 1663-45-2, mainly applied to tetrahedral copper complex preparation electrocatalyst reduction proton dihydrogen preparation; electrochem redox tetrahedral copper complex, SDS of cas: 1663-45-2.

Four copper(I) complexes [Cu(MeCN)4]PF6 (1), [Cu(dppe)2]PF6 (2), [Cu(bpy)2]PF6 (3) and [Cu(bpy)(dppe)]PF6 (4) have been used as electrocatalysts in the generation of dihydrogen from proton reduction Low overpotentials of 0.4 V have been measured using cyclic voltammetry when 1 and 3 were used as the catalysts in the presence of acetic acid as the proton source in acetonitrile. In contrast, a higher overpotential is observed for 4 while 2 is unable to catalyze the process. A mechanism for proton reduction has been proposed.

Here is a brief introduction to this compound(1663-45-2)SDS of cas: 1663-45-2, if you want to know about other compounds related to this compound(1663-45-2), you can read my other articles.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Application of 1663-45-2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1,2-Bis(diphenylphosphino)ethane, is researched, Molecular C26H24P2, CAS is 1663-45-2, about Novel base-free dianion complexes of Pt(II) and Pd(II) derived from heterocyclic thiourea and tertiary phosphine ligands. Author is Faihan, Ahmed S.; Al-Jibori, Subhi A.; Al-Janabi, Ahmed S..

Treatment of one molar equivalent of [M(HCPPT)2] (M = Pd, Pt; H2CPPT = 1-(5-chloropyridin-2-yl)-3-phenylthiourea) with one molar equivalent of κ2-diphos (diphos = dppe, dppp, dppb, and dppf) or two molar equivalent of κ1-phos afforded eight heterocyclic thiourea dianion complexes (1-8). The spectroscopic data anal. showed clear AX splitting pattern, which indicates that the two coordinated phosphorus atoms are non-equivalent Meaning that, the metal’s center is attached to both S,N donor atoms in a chelating fashion. In addition, the splitting system show a good resemblance to the previously synthesized thiourea dianion complexes. Furthermore, the reaction is believed to undergo a square planar substitution mechanism at which five coordinate intermediate is formed. Generally, the reported complexes (1-8) are believed to resemble their analogs thiourea dianion complexes at which a four membered ring structure is formed with Pt(II) or Pd(II) being centered, adopting a square planar geometry. Four of the synthesized complexes (1-4) were tested against Salmonella typhimurium and Bacillus subtilis bacteria at which complexes 4 and 2 showed highest activity values.

Here is a brief introduction to this compound(1663-45-2)Application of 1663-45-2, if you want to know about other compounds related to this compound(1663-45-2), you can read my other articles.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Sun, Feilong; Yang, Chengxi; Ni, Jie; Cheng, Gui-Juan; Fang, Xianjie researched the compound: 1,2-Bis(diphenylphosphino)ethane( cas:1663-45-2 ).Application In Synthesis of 1,2-Bis(diphenylphosphino)ethane.They published the article 《Ligand-Controlled Regiodivergent Nickel-Catalyzed Hydrocyanation of Silyl-Substituted 1,3-Diynes》 about this compound( cas:1663-45-2 ) in Organic Letters. Keywords: nickel catalyzed hydrocyanation silyl substituted diyne; crystal structure cyano containing enyne; mol structure cyano containing enyne; cyano silyl containing enyne preparation crystal structure. We’ll tell you more about this compound (cas:1663-45-2).

A regiodivergent Ni-catalyzed hydrocyanation of 1-aryl-4-silyl-1,3-diynes is reported. When appropriate bisphosphine and phosphine-phosphite ligands are applied, the same starting materials can be converted into two different enynyl nitriles with good yields and high regioselectivities. The DFT calculations unveiled that the structural features of different ligands bring divergent alkyne insertion modes, which in turn lead to different regioselectivities. Also, the synthetic value of the cyano-containing 1,3-enynes was demonstrated with several downstream transformations.

Here is a brief introduction to this compound(1663-45-2)Application In Synthesis of 1,2-Bis(diphenylphosphino)ethane, if you want to know about other compounds related to this compound(1663-45-2), you can read my other articles.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Electric Literature of C26H24P2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1,2-Bis(diphenylphosphino)ethane, is researched, Molecular C26H24P2, CAS is 1663-45-2, about Excitation-Wavelength-Dependent and Auxiliary-Ligand-Tuned Intersystem-Crossing Efficiency in Cyclometalated Platinum(II) Complexes: Spectroscopic and Theoretical Studies.

Understanding the factors affecting the intersystem-crossing (ISC) rate constant (kISC) of transition-metal complexes is crucial to material design with tailored photophys. properties. Most of the works on ISC to date focused on the influence by the chromophoric ligand and the understanding of the ISC efficiency were mainly drawn from the steady-state fluorescence to phosphorescence intensity ratio and ground-state calculations, with only a few high-level calculations on kISC that take excited-state structural change and solvent reorganization into account for quant. comparisons with the exptl. data. In this work, a series of [Pt(thpy)X]+ complexes were prepared [Hthpy = 2-(2′-thienyl)pyridine, where X = auxiliary ligands] and characterized by both steady-state and time-resolved luminescence spectroscopies. A panel of auxiliary ligands with varying σ-donating/π-accepting character have been used. For comparison, analogs of [Pt(ppy)(P P)]+ (Hppy = 2-phenylpyridine and P P = diphosphino ligand) were also examined The [Pt(thpy)(P P)]+ complexes exhibit dual fluorescence-phosphorescence emission, with their ISC rate constants varied with the electronic characteristics of the auxiliary ligand: the more electron-donating ligand induces faster ISC from the S1 excited state to the triplet manifold. D. functional theory (DFT)/time-dependent DFT calculations of kISC(S1→T2) at the optimized excited-state geometries give excellent quant. agreement with the femtosecond time-resolved fluorescence measurements; it was revealed that the more electron-donating auxiliary ligand increases metal contributions to both occupied and virtual orbitals and decreases the energy gap of the coupling excited states, leading to a decrease in the activation energy and an increase in spin-orbit coupling. Furthermore, the ISC rate constants of [Pt(thpy)(P P)]+ complexes are found to depend on the excitation wavelengths. The deviation from Kasha-Vavilov′s rule upon photoexcitation at λexc < 350 nm is due to the ultrafast S2 → T2 and S2 → T3 ISCs, as demonstrated by the calculated τISC < 100 fs, giving hints as to why S2 → S1 internal conversion (τIC ∼ ps) is not competitive with this hyper-ISC. Control of the intersystem-crossing (ISC) rate constant is key to tailoring the emission properties of transition-metal complexes. Both spectroscopic and theor. studies of a series of cyclometalated platinum(II) complexes reveal that the ISC rate can be tuned by varying the electron-donating capability of the auxiliary ligands. Moreover, hyper-ISC from the higher-lying singlet excited state to the triplet manifold has been unveiled by theor. studies, explaining the excitation-wavelength-dependent dual fluorescence-phosphorescence emission for the present platinum(II) complexes. Here is a brief introduction to this compound(1663-45-2)Electric Literature of C26H24P2, if you want to know about other compounds related to this compound(1663-45-2), you can read my other articles.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Related Products of 1663-45-2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1,2-Bis(diphenylphosphino)ethane, is researched, Molecular C26H24P2, CAS is 1663-45-2, about Synthesis, crystallographic studies, antibacterial and antifungal activities of mononuclear mercury(II) complexes derived from [PPh2(CH2)nPPh2CH2C(O)C6H4Cl]Br ligands.

This account describes authors recent studies on zwitterionic mercury(II) complexes with two diphosphonium salts, [PPh2(CH2)nPPh2CH2C(O)C6H4Cl]Br (n = 1 (S1) and 2 (S2)), derived from 1,2-bis(diphenyl-phosphino)methane (dppm) and 1,2-bis(diphenyl-phosphino)ethane (dppe). These complexes were synthesized through reactions between diphosphonium salts and HgX2 in equimolar ratio and characterized by elemental anal., IR, 1H, 13C and 31P NMR spectroscopic methods. The structure of complex [HgI2Br(PPh2(CH2)2PPh2CH2C(O)C6H4Cl)] (6) was determined by a single crystal x-ray structural anal. The results indicated that the mercury center in this complex is four-coordinated in a distorted tetrahedral configuration. The results confirmed that the coordination of ligand to metal occurred through the phosphine group (P-coordination mode). Furthermore, antibacterial/antifungal activities of the diphosphonium ligands and their complexes were tested against two Gram-neg. bacteria Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 9027) and two Gram-pos. bacteria Staphylococcus aureus (ATCC 6538) and Bacillus subtilis (ATCC 6633) as well as two fungi (Geotrichum sp. and Candida albicans). It seems that the chem. compounds reported herein may be used for control of pathogenic bacteria/fungi.

If you want to learn more about this compound(1,2-Bis(diphenylphosphino)ethane)Related Products of 1663-45-2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1663-45-2).

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Han, Peilin; Han, Huijuan; Zhang, Xiaowei; Hou, Xiaoxiao; Wang, Hui; Liu, Chunhui published an article about the compound: 1,2-Bis(diphenylphosphino)ethane( cas:1663-45-2,SMILESS:P(CCP(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4 ).Application of 1663-45-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1663-45-2) through the article.

The competing mechanisms of silver-/aminolithium-catalyzed hydrofunctionalization of α,β-unsaturated ester with an amino alc. have been systematically studied with the DFT methods. Here, the acidity of a weaker nucleophile OH group of an amino alc. is significantly higher than that of NH2 group, so it is easy to deprotonate by Ag(HMDS)/dppe. However, the generated Ag-O bond is more stable than the corresponding Ag-N bond. Therefore, the OH group shows higher reactivity than the NH2 group in the presence of a Lewis acid/Bronsted base pair catalyst. Then, α,β-unsaturated esters can be inserted into corresponding Ag-O bonds to obtain alkyl silver species. Alkyl silver can be protonated by bis(trimethylsilyl)amines to obtain hydrogen functionalized products and regenerate silver amino active compounds Ag(HMDS)/dppe.

If you want to learn more about this compound(1,2-Bis(diphenylphosphino)ethane)Application of 1663-45-2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1663-45-2).

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

COA of Formula: C26H24P2. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 1,2-Bis(diphenylphosphino)ethane, is researched, Molecular C26H24P2, CAS is 1663-45-2, about The palladacycle, BTC2, exhibits anti-breast cancer and breast cancer stem cell activity. Author is Kimani, Serah; Chakraborty, Suparna; Irene, Ikponmwosa; de la Mare, Jo; Edkins, Adrienne; du Toit, Andre; Loos, Ben; Blanckenberg, Angelique; Van Niekerk, Annick; Costa-Lotufo, Leticia V.; ArulJothi, KN.; Mapolie, Selwyn; Prince, Sharon.

In women globally, breast cancer is responsible for most cancer-related deaths and thus, new effective therapeutic strategies are required to treat this malignancy. Platinum-based compounds like cisplatin are widely used to treat breast cancer, however, they come with limitations such as poor solubility, adverse effects, and drug resistance. To overcome these limitations, complexes containing other platinum group metals such as palladium have been studied and some have already entered clin. trials. Here we investigated the anti-cancer activity of a palladium complex, BTC2, in MCF-7 estrogen receptor pos. (ER+) and MDA-MB-231 triple neg. (TN) human breast cancer cells as well as in a human breast cancer xenograft chick embryo model. BTC2 exhibited an average IC50 value of 0.54μM, a desirable selectivity index of >2, inhibited the migration of ER+ and TN breast cancer cells, and displayed anti-cancer stem cell activity. We demonstrate that BTC2 induced DNA double strand breaks (increased levels of γ-H2AX) and activated the p-ATM/p-CHK2 and p-p38/MAPK pathways resulting in S- and G2/M-phase cell cycle arrests. Importantly, BTC2 sensitized breast cancer cells by triggering the intrinsic (cleaved caspase 9) and extrinsic (cleaved caspase 8) apoptotic as well as necroptotic (p-RIP3 and p-MLKL) cell death pathways and inhibiting autophagy and its pro-survival role. Furthermore, in the xenograft in vivo model, BTC2 displayed limited toxicity and arrested the tumor growth of breast cancer cells over a 9-day period in a manner comparable to that of the pos. control drug, paclitaxel. BTC2 thus displayed promising anti-breast cancer activity.

If you want to learn more about this compound(1,2-Bis(diphenylphosphino)ethane)COA of Formula: C26H24P2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1663-45-2).

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis