In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system. 108-47-4,108-47-4, name is 2,4-Dimethylpyridine. In an article，Which mentioned a new discovery about 108-47-4
Bronsted acid catalyzed functionalization of sp3 C – H bonds in 2-methyl azaarenes has been achieved in the reaction with isatins. This method provides facile synthesis of biologically important azaarene-substituted 3-hydroxy-2-oxindoles in one step in moderate to good yields.
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Reference：
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis