Month: April 2022

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-(4-Pyridyl)-1H-tetrazole, is researched, Molecular C6H5N5, CAS is 14389-12-9, about (E)-1,2-Bis(5-aryl-1,3,4-oxadiazol-2-yl)ethenes, the main research direction is ethylenebisoxadiazole preparation; oxadiazole ethylenebis preparation; tetrazole fumaroyl chloride Huisgen.HPLC of Formula: 14389-12-9.

The title compounds (I) were prepared by acylation of the corresponding tetrazoles with fumaryl chloride and subsequent thermal ring transformation. The modified Huisgen reaction renders a new pathway to 3-(1,3,4-oxadiazol-2-yl)propenoic acids and subsequently to I with different substituents.

Compounds in my other articles are similar to this one(5-(4-Pyridyl)-1H-tetrazole)HPLC of Formula: 14389-12-9, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

COA of Formula: C26H24P2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1,2-Bis(diphenylphosphino)ethane, is researched, Molecular C26H24P2, CAS is 1663-45-2, about Fluorinated Cycloplatinated(II) Complexes Bearing Bisphosphine Ligands as Potent Anticancer Agents. Author is Shahsavari, Hamid R.; Hu, Jiyun; Chamyani, Samira; Sakamaki, Yoshie; Aghakhanpour, Reza Babadi; Salmon, Christopher; Fereidoonnezhad, Masood; Mojaddami, Ayyub; Peyvasteh, Parnian; Beyzavi, Hudson.

A family of cationic cycloplatinated(II) complexes [Pt(dfppy)(P^P)]Cl incorporating bisphosphine ligands was prepared: (dfppy = 2-(2,4-difluorophenyl)pyridine; P^P = bis(diphenylphosphino)methane (1, dppm), 1,2-bis(diphenylphosphino)ethane (2, dppe), 1,2-bis(diphenylphosphino)benzene (3, dppbz)). The complexes were characterized by several anal. and spectroscopic methods. These complexes displayed acceptable stability in biol. environments, which was confirmed by NMR, HR ESI-MS, and UV-visible techniques. The antiproliferative properties of these complexes were evaluated by the National Cancer Institute (NCI) against 60 different human tumor cell lines such as leukemia, melanoma, lung, colon, brain, ovary, breast, prostate, and kidney. These complexes showed higher cytotoxicity in comparison to cisplatin against a wide variety of cancer cell lines such as K-562 (leukemia), HOP-92 (lung), HCT-116 (colon), OVCAR-8 (ovarian), PC-3 (prostate), MDA-MB-468 (breast), and melanoma cancer cell lines. Complex 3, as the most potent compound furnished an excellent antiproliferative activity in comparison to cisplatin against Hela, SKOV3, and MCF-7 cancer cell lines. The main mode of the interactions of 1-3 with DNA was also determined using mol. docking studies.

Compounds in my other articles are similar to this one(1,2-Bis(diphenylphosphino)ethane)COA of Formula: C26H24P2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-(4-Pyridyl)-1H-tetrazole, is researched, Molecular C6H5N5, CAS is 14389-12-9, about Solvothermal Synthesis and Diverse Coordinate Structures of a Series of Luminescent Copper(I) Thiocyanate Coordination Polymers Based on N-Heterocyclic Ligands, the main research direction is copper thiocyanate aminopyridyltriazole pyridyltetrazole pyridylbenzimidazole polymeric complex preparation structure; crystal structure copper thiocyanate aminopyridyltriazole pyridyltetrazole pyridylbenzimidazole polymeric complex; luminescence copper thiocyanate aminopyridyltriazole pyridyltetrazole pyridylbenzimidazole polymeric complex; thermal decomposition copper thiocyanate aminopyridyltriazole pyridyltetrazole pyridylbenzimidazole polymeric complex.Safety of 5-(4-Pyridyl)-1H-tetrazole.

Solvothermal reactions of CuSCN with 4-amino-3,5-bis(3-pyridyl)-1,2,4-triazole (3-Abpt), 5-(4-pyridyl)tetrazole (4-Ptz), and 2-(n-pyridyl)benzimidazole (n-PyHBIm, n = 4, 3, 2) in MeCN afford six novel coordination polymers: [Cu5(SCN)5(3-Abpt)2]n (1), [Cu(SCN)(3-Abpt)]n (2), [Cu(SCN)(4-Ptz)]n (3), [Cu2(SCN)2(4-PyHBIm)]n (4), [Cu2(SCN)2(3-PyHBIm)]n (5), and [Cu2(SCN)2(2-PyBIm)(2-PyHBIm)]n (6). All these complexes were structurally characterized by x-ray diffraction anal. 1 Is the 1st example of a 1,1,1,3-μ4-tetradentate thiocyanate complex which displays a three-dimensional (3D) polymeric framework constructed from thiocyanate and tetradentate 3-Abpt. 2 Exhibits a two-dimensional (2D) 4.82 network constructed from unidentate thiocyanate and tridentate 3-Abpt. 3 Is a 1-dimensional (1D) ladder-like double-chain polymer assembled by bidentate thiocyanate and 4-Ptz ligands. 4 Shows a 2-dimensional 1,1,3-μ3-thiocyanate Cu 4.82 network where bidentate 4-PyHBIm locates at both sides of the 2-dimensional layer. 5 Displays a 2-dimensional 63 network constructing from 1,1,3-μ3-thiocyanate and bidentate 3-PyHBIm. 6 Is a 1-dimensional 21 helical chain polymer constructing from 1,3-μ2-thiocyanate and 2-PyBIm anion. Bond valence sum (BVS) anal. and magnetic susceptibility indicate that 6 is a mixed-valence compound The coordinate diversity of thiocyanate is discussed. 1-6 Are all thermally stable up to 230-290°. They exhibit yellow or blue luminescence originating from ligand-to-metal charge transfer or ligand-centered emission.

Compounds in my other articles are similar to this one(5-(4-Pyridyl)-1H-tetrazole)Safety of 5-(4-Pyridyl)-1H-tetrazole, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1,5-Dibromopentane( cas:111-24-0 ) is researched.Computed Properties of C5H10Br2.Liang, Yan; He, Dian; Zhou, Deshun; Li, Junshuai; Tang, Lei; Wang, Zhen published the article 《Synthesis, Antibacterial and Pharmacokinetic Evaluation of Novel Derivatives of Harmine N9-Cinnamic Acid》 about this compound( cas:111-24-0 ) in Molecules. Keywords: harmine cinnamic acid derivative antibacterial pharmacokinetic evaluation; antibacterial activity; harmine; pharmacokinetics; synthesis. Let’s learn more about this compound (cas:111-24-0).

A series of 16 new derivatives of harmine N9-Cinnamic acid were synthesized and fully characterized using NMR and MS. The in vitro antibacterial evaluation revealed that most of the synthesized harmine derivatives displayed better antibacterial activities against Gram-pos. strains (S. aureus, S. albus and MRSA) than Gram-neg. strains (E. coli and PA). In particular, compound 3c showed the strongest bactericidal activity with a min. inhibitory concentration of 13.67 μg/mL. MTT assay showed that compound 3c displayed weaker cytotoxicity than harmine with IC50 of 340.30, 94.86 and 161.67 μmol/L against WI-38, MCF-7 and HepG2 cell lines, resp. The pharmacokinetic study revealed that the distribution and elimination of 3c in vivo were rapid in rats with an oral bioavailability of 6.9%.

Compounds in my other articles are similar to this one(1,5-Dibromopentane)Computed Properties of C5H10Br2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Safety of 1,5-Dibromopentane. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 1,5-Dibromopentane, is researched, Molecular C5H10Br2, CAS is 111-24-0, about Synthesis and characterization of new gemini surfactants derived from imidazole and indole and study their efficiency as dispersible and biologically effective materials. Author is Al. Ibadi, Ghufran A. M.; Al. Asadi, Mohanad J. K..

In the present study, two sets of stimulants for the gemini surfactants derived from imidazole and indole were prepared, which contain a terminal chain containing eight carbon atoms and a separation between the two heads and two tails of the surface activating substance called 1, 5-di bromo pentane. The prepared compounds were characterized using the FTIR and 1HNMR. The value of the critical micellization concentration (CMC) was calculated using elec. conductivity, as well as the value of the balance system between hydrophilic and lipophilic groups (HLB) to find out the appropriate application for them. The effectiveness of dispersion of oil spots in (oil/water) emulsions and biol. activity on specific types of bacteria have also been studied.

Compounds in my other articles are similar to this one(1,5-Dibromopentane)Safety of 1,5-Dibromopentane, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Electric Literature of C6H5N5. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 5-(4-Pyridyl)-1H-tetrazole, is researched, Molecular C6H5N5, CAS is 14389-12-9, about Facile, highly efficient and novel method for synthesis of 5-substituted 1H-tetrazoles catalysed by. Author is Esirden, Ibrahim; Basar, Erhan; Kaya, Muharrem.

A series of 5-substituted 1H-tetrazole derivatives I [R = 4-pyridinyl, 4-O2NC6H4, 4-acetamidophenyl, etc.] was synthesized via copper(I) chloride catalyzed [3+2] cycloaddition of aryl nitriles with sodium azide. The salient features of this protocol were short reaction times, high yields, environmental friendly catalyst and simple procedure.

Compounds in my other articles are similar to this one(5-(4-Pyridyl)-1H-tetrazole)Electric Literature of C6H5N5, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1,5-Dibromopentane( cas:111-24-0 ) is researched.Recommanded Product: 1,5-Dibromopentane.Mezzetta, Andrea; Guglielmero, Luca; Mero, Angelica; Tofani, Giorgio; D’Andrea, Felicia; Pomelli, Christian Silvio; Guazzelli, Lorenzo published the article 《Expanding the Chemical Space of Benzimidazole Dicationic Ionic Liquids》 about this compound( cas:111-24-0 ) in Molecules. Keywords: benzimidazole dicationic ionic liquid thermal stability cyclic voltammetry; benzimidazole; cyclic voltammetry; dicationic ionic liquids; green solvents; ionic liquids; thermal behavior; thermal stability. Let’s learn more about this compound (cas:111-24-0).

Benzimidazole dicationic ionic liquids (BDILs) have not yet been widely explored in spite of their potential. Therefore, two structurally related families of BDILs, paired with either bromide or bistriflimide anions and bearing alkyl spacers ranging from C3 to C6, have been prepared Their thermal properties have been studied by thermogravimetric anal. (TGA) and differential scanning calorimetry (DSC), while their elec. properties have been assessed by cyclic voltammetry (CV). TG anal. confirmed the higher stability of the bistriflimide BDILs over the bromide BDILs, with minor variation within the two families. Conversely, DSC and CV allowed for ascertaining the role played by the spacer length. In particular, the thermal behavior changed dramatically among the members of the bistriflimide family, and all three possible thermal behavior types of ILs were observed Furthermore, cyclic voltammetry showed different electrochem. window (C3(C1BenzIm)2/2Tf2N < C4(C1BenzIm)2/2Tf2N, C5(C1BenzIm)2/2Tf2N < C6(C1BenzIm)2/2Tf2N) as well as a reduction peak potential, shape, and intensity as a function of the spacer length. The results obtained highlight the benefit of accessing a more structurally diverse pool of compounds offered by dicationic ILs when compared to the parent monocationic ILs. In particular, gains are to be found in the ease of fine-tuning their properties, which translates in facilitating further investigations toward BDILs as designer solvents and catalysts. Compounds in my other articles are similar to this one(1,5-Dibromopentane)Recommanded Product: 1,5-Dibromopentane, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Ji, Radhe Shyam; Raghuvanshi, Abhinav; Jha, Badrinath; Mathur, Pradeep published the article 《Reactions of [Ru6(μ6–C)(C6H5CH3)(CO)14]: Synthesis of some new Ru-Pt carbonyl clusters and diphosphine substitution》. Keywords: carbido ruthenium carbonyl cluster reaction platinum diphosphine; crystal mol structure carbido ruthenium carbonyl platinum diphosphine complex.They researched the compound: 1,2-Bis(diphenylphosphino)ethane( cas:1663-45-2 ).Application of 1663-45-2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1663-45-2) here.

Three new RuPt clusters [Ru6Pt(μ6-C)(C6H5CH3)(CO)13(COD)] (2), [Ru6Pt(μ6-C)(C6H5CH3)(CO)14(PPh3)] (3) and [Ru6Pt2(μ6-C)(C6H5CH3)(CO)13(PPh3)3] (4) were obtained from the reaction of [Ru6(μ6-C)(C6H5CH3)(CO)14] (1) with two different Pt precursors. Both 2 and 3 consists of a Ru6Pt cluster with face capped octahedron metal core, whereas, 4 has a unique Ru6Pt2 cluster core structure with doubly capped octahedron. Further, CO substitution behavior of 1 was studied with diphosphine ligands, which results in the formation of mono and bi substituted products, which also show the removal of the toluene cap by the dppe ligand. All the compounds were characterized structurally by x-ray diffraction anal.

Compounds in my other articles are similar to this one(1,2-Bis(diphenylphosphino)ethane)Application of 1663-45-2, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Tri(naphthalen-1-yl)phosphine( cas:3411-48-1 ) is researched.Category: chiral-nitrogen-ligands.Schiemenz, Gunter Paulus; Naether, Christian; Poerksen, Simon published the article 《peri-Interactions in naphthalenes, 9. On hypercoordination in non-quaternary phosphonium salts and a secondary phosphine with the (8-dimethylamino-naphth-1-yl) substituent》 about this compound( cas:3411-48-1 ) in Zeitschrift fuer Naturforschung, B: Chemical Sciences. Keywords: phosphine protonation tertiary phosphonium proton phosphorus coupling constant; aminonaphthyl phosphine preparation protonation nitrogen phosphorus peri interaction; crystal structure secondary dimethylamino naphthyl phosphine; mol structure secondary dimethylamino naphthyl phosphine. Let’s learn more about this compound (cas:3411-48-1).

The 31P NMR data of non-quaternary (8-dimethylamino-naphth-1-yl)phosphonium salts, with emphasis on the 1J(31P, 1H) coupling constants, where scrutinized for their potential to yield information about N-P dative interactions. As for δ(29Si) and 1J(29Si, 1H) in the isosteric silanes, the data do not permit conclusions in favor of such interactions. 1J(31P, 1 H) of bis(8-dimethylaminonaphthalen-l-yl)phosphine in conjunction with the distances d(N···P) invalidates the basic assumption on which the claim of dative N→P/Si bonding in such phosphorus and silicon compounds rests, viz. that N···P/Si distances of ca. 270 pm are evidence for P/Si-hypercoordination. No evidence for hydrogen bonds N···H-P was found.

Compounds in my other articles are similar to this one(Tri(naphthalen-1-yl)phosphine)Category: chiral-nitrogen-ligands, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis

Computed Properties of C30H21P. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Tri(naphthalen-1-yl)phosphine, is researched, Molecular C30H21P, CAS is 3411-48-1, about Arylalkene Synthesis via Decarboxylative Cross-Coupling of Alkenyl Halides. Author is Tang, Jie; Goossen, Lukas J..

A bimetallic catalyst system generated from readily available palladium(II) and copper(I) salts, 1,10-phenanthroline and tri-1-naphthylphosphine was found to efficiently mediate the decarboxylative cross-coupling of alkenyl bromides and chlorides with aromatic carboxylates. It allows the regiospecific synthesis of a broad range of aryl- and heteroarylalkenes in high yields.

Compounds in my other articles are similar to this one(Tri(naphthalen-1-yl)phosphine)Computed Properties of C30H21P, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Chiral nitrogen ligands in late transition metal-catalysed asymmetric synthesis—I. Addressing the problem of ligand lability in rhodium-catalysed hydrosilations,
Nitrogen-Containing Ligands for Asymmetric Homogeneous and Heterogeneous Catalysis